Intraocular tumors in animals. II. Primary nonpigmented intraocular tumors.

The present authors (14) have recently discussed intraocular tumors in animals, in a report restricted to primary pigmented neoplasms and based on fifteen such cases in dogs. This was the first comprehensive study of spontaneous intraocular tumors in animals, but because of its restricted scope there remain for consideration other primary and various secondary intraoeular tumors. In the present study we are concerned with primary nonpigmented tumors. Secondary tumors will be discussed in a companion paper. 1 Review of literature.--Published reports on primary intraocular tumors in animals are rather scanty. Those on pigmented tumors have already been reviewed (14). There are three reports on retinoblastomas in horses (~, 6, 10) and one each in a calf (8), a dog (4), a cat (7), a monkey (~), and a chicken (5). Of these, only the reports of Fr (6) dealing with horses and of Cole (5) with the chicken are sufficiently detailed to permit appraisal, and both meet the diagnostic criteria for retinoblastomas. A hemangioma of the iris of a dog was reported by Magrane (9) and submitted by him to the Armed Forces Institute of Pathology. Another case of vascular tumor was seen in the iris of a chicken by Ball (1) and termed by him hemangioendothelioma. Such tumors occur rarely in man; Reese (11) stated that only nine cases have been reported but that six of these are not acceptable. Since so few cases of hemangioma are on record, either from animals or man, we are redescribing (with his permission) Magrane's case herein in somewhat greater detail. Tumors of smooth muscle arising from the intraocular structures appear to be rare in man. Reese (11) accepted only three reports unequivocally, and several others with reservations.